Home > Product > Antibody > Rabbit Anti-C21orf66/FITC Conjugated antibody
BM 020; BM020; Chromosome 21 open reading frame 66; FSAP105; Functional spliceosome-associated protein 105; GC rich sequence DNA binding factor candidate; GC-rich sequence DNA-binding factor 1; GCFC; GCFC1; PAXB1_HUMAN; PAX3 and PAX7 binding pro
Cat:
SL13758R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human C21orf66
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
105kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
C21orf66, also known as GCFC (GSLCrich sequence DNA-binding factor), is a 917 amino acid protein that localizes to the nucleus and belongs to the GCF family. Expressed ubiquitously, C21orf66 functions as a possible transcription factor and exists as four alternatively spliced isoforms, designated A, B, C and D. The gene encoding C21orf66 maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer's Disease, amyotrophic lateral sclerosis and, most notably, Down Syndrome (also known as trisomy 21.

Function:
Possible transcription factor.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the GCF family.

Database links:

Entrez Gene: 94104 Human

SwissProt: Q9Y5B6 Human

Unigene: 68804 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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