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Rabbit Anti-FAM172A/FITC Conjugated antibody
background:
FAM172A is a 416 amino acid secreted protein belonging to the UPF0528 family and is encoded by a gene located on human chromosome 5. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Subcellular Location:
Secreted.
Similarity:
Belongs to the UPF0528 family.
Database links:
Entrez Gene: 83989 Human
Entrez Gene: 68675 Mouse
Entrez Gene: 29926 Rat
SwissProt: Q8WUF8 Human
SwissProt: Q3TNH5 Mouse
Unigene: 600086 Human
Unigene: 343005 Mouse
Unigene: 203242 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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