background:
This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of SLCtype lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Function:
Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen
Subcellular Location:
Membrane.
Post-translational modifications:
N-glycosylated.
Similarity:
Contains 1 SLCtype lectin domain.
Database links:
Entrez Gene: 140578 Human
Entrez Gene: 29248 Mouse
Entrez Gene: 288289 Rat
Omim: 607247 Human
SwissProt: Q9H9P2 Human
SwissProt: Q9CXM0 Mouse
Unigene: 283725 Human
Unigene: 77895 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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