Home > Product > Antibody > Rabbit Anti-COPG2/FITC Conjugated antibody
2 COP; Coat protein nonclathrin gamma 2 cop; Coatomer protein complex subunit gamma 2; Coatomer subunit gamma 2; Coatomer subunit gamma-2; COPG 2; Copg2; COPG2_HUMAN; DKFZp761N09121; FLJ11781; Gamma 2 coat protein; Gamma 2 COP; Gamma-2-coat pr
Cat:
SL13979R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,)
Immunogen:
KLH conjugated synthetic peptide derived from human COPG2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
98kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Subcellular Location:
Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.

Similarity:
Belongs to the COPG family.
Contains 6 HEAT repeats.

Database links:

Entrez Gene: 26958 Human

Entrez Gene: 54160 Mouse

Entrez Gene: 58847 Rat

Omim: 604355 Human

SwissProt: Q9USF2 Human

SwissProt: Q9QXK3 Mouse

Unigene: 6421 Human

Unigene: 381860 Mouse

Unigene: 39896 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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