background:
CTRP3 is a type I cell surface glycoprotein that mediates the enhancement of phagocytic activity. CTRP3 binds to several ligands, including the complement protein C1q, mannose-binding lectin (MBL), and pulmonary surfactant protein A (SPA). CTRP3 is expressed in cells of myeloid lineage, endothelial cells, and platelets. In addition to its role in phagocytosis, CTRP3 may be involved in cellular adhesion. Complement C1q tumor necrosis factor-related protein 3 (CTRP3), also known as CORS26, has a trimeric structure and can assemble into hexameric or higher order molecular forms.
Subcellular Location:
Secreted.
Similarity:
Contains 1 C1q domain.
Contains 1 collagen-like domain.
Database links:
Entrez Gene: 114899 Human
Entrez Gene: 81799 Mouse
Entrez Gene: 29966 Rat
Omim: 612045 Human
SwissProt: Q9BXJ4 Human
SwissProt: Q9ES30 Mouse
Unigene: 171929 Human
Unigene: 280158 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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