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Rabbit Anti-CTTNBP2NL/FITC Conjugated antibody
background:
CTTNBP2NL is a 639 amino acid protein that is encoded by a gene that maps to human chromosome 1p13.2. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Database links:
Entrez Gene: 55917 Human
Entrez Gene: 80281 Mouse
Entrez Gene: 310760 Rat
SwissProt: Q9P2B4 Human
SwissProt: Q99LJ0 Mouse
SwissProt: D4A8X8 Rat
Unigene: 725947 Human
Unigene: 200327 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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