Home > Product > Antibody > Rabbit Anti-DHTKD1/FITC Conjugated antibody
Dehydrogenase E1 and transketolase domain containing 1; Dehydrogenase E1 and transketolase domain containing protein 1; Dehydrogenase E1 and transketolase domain-containing protein 1; DHTK1_HUMAN; dhtkd1; DKFZp762M115; KIAA1630; MGC3090; Probable
Cat:
SL14310R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human DHTKD1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
103kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a component of a mitochondrial 2-oxoglutarate-dehydrogenase-complex-like protein involved in the degradation pathways of several amino acids, including lysine. Mutations in this gene are associated with 2-aminoadipic 2-oxoadipic aciduria and Charcot-Marie-Tooth Disease Type 2Q. [provided by RefSeq, May 2013]

Function:
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the alpha-ketoglutarate dehydrogenase family.

Database links:

Entrez Gene: 55526 Human

Entrez Gene: 209692 Mouse

SwissProt: Q96HY7 Human

SwissProt: A2ATU0 Mouse

Unigene: 104196 Human

Unigene: 71228 Human

Unigene: 222517 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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