Rabbit Anti-DMRT1/FITC Conjugated antibody

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DM domain expressed in testis 1; DM domain expressed in testis protein 1; DMRT 1; dmrt1; DMRT1_HUMAN; DMT 1; DMT1; Doublesex and mab 3 related transcription factor 1; Doublesex- and mab-3-related transcription factor 1.

Cat:

SL14346R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DMRT1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

39kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Function:
May be required for testis development.

Subcellular Location:
Nucleus.

Tissue Specificity:
Testis specific.

Similarity:
Belongs to the DMRT family.
Contains 1 DM DNA-binding domain.

Database links:

Entrez Gene: 1761 Human

Omim: 602424 Human

SwissProt: Q9Y5R6 Human

Unigene: 98586 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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