Home > Product > Antibody > Rabbit Anti-DNAH6/FITC Conjugated antibody
axonemal; Axonemal beta dynein heavy chain 6; Ciliary dynein heavy chain 6; DNAH6; Dnahc6; DNHL1; DYH6_HUMAN; Dynein heavy chain 6; FLJ37357; HL-2.
Cat:
SL14366R-FITC
Species Reactivity:
Rat,(predicted: Human,Mouse,)
Immunogen:
KLH conjugated synthetic peptide derived from human DNAH6
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
476kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major classes of dyneins, axonemal and cytoplasmic, have been identified. DNAH6 is an axonemal dynein heavy chain (DHC) (Vaughan et al., 1996 [PubMed 8812413]).[supplied by OMIM, Mar 2008]

Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.

Subcellular Location:
Cytoplasm; cytoskeleton; cilium axoneme.

Tissue Specificity:
Detected in brain, testis and trachea.

Similarity:
Belongs to the dynein heavy chain family.

Database links:

Entrez Gene: 1768 Human

Omim: 603336 Human

SwissProt: Q9C0G6 Human

Unigene: 249972 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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