Rabbit Anti-DNAJB14/FITC Conjugated antibody

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5730496F10Rik; DJB14_HUMAN; DnaJ (Hsp40) homolog, subfamily B, member 14; DnaJ homolog subfamily B member 14; dnajb14; EGNR9427; FLJ14281; MGC22187; PRO34683; UNQ9427/PRO34683.

Cat:

SL14372R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNAJB14

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The DnaJ family, one of the largest of all the chaperone families, has evolved with diverse cellular localization and functions. The presence of a J domain defines a protein as a member of the DnaJ family. DnaJ heat-shock induced proteins are derived from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. Members of this family contain cysteine-rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for chaperone function. DnaJ family members are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJB14 (DnaJ (Hsp40) homolog, subfamily B, member 14) is a 379 amino acid single-pass membrane protein containing one J domain and is thought to act as a co-chaperone. DnaJB14 exists as two alternatively spliced isoforms.

Function:
May act as a co-chaperone.

Subcellular Location:
Membrane.

Similarity:
Contains 1 J domain.

Database links:

Entrez Gene: 79982 Human

SwissProt: Q8TBM8 Human

Unigene: 577426 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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