Rabbit Anti-DNAJC1/FITC Conjugated antibody

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DnaJ (Hsp40) homolog subfamily C member 1; DnaJ homolog subfamily C member 1; DnaJ like protein; DnaJ protein homolog MTJ1; Dnajc1; DNAJL1; DNJC1_HUMAN; ERdj1; HTJ1; MGC131954; MTJ1.

Cat:

SL14377R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNAJC1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

59kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The DnaJ family comprises a group of chaperone proteins that contain a J domain and have diverse cellular localization and functions. DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis and are also important mediators of proteolysis and protein degradation. DnaJC1 (DnaJ homolog subfamily C member 1), also designated MTJ1, HTJ1, ERdj1 or DNAJL1, is a 554 amino acid single-pass type I membrane protein found in the membrane of the endoplasmic reticulum, nucleus and microsome. DnaJC1 contains one J domain and two SANT domains, through which it interacts with GRP 78 and AACT, respectively. Via its cytosolic domain, DnaJC1 interacts with ribosomes and likely modulates protein synthesis. The gene encoding DnaJC1 maps to human chromosome 10p12.31 and mouse chromosome 2 A3.

Function:
May modulate protein synthesis.

Subcellular Location:
Endoplasmic reticulum membrane. Nucleus membrane. Microsome membrane.

Similarity:
Contains 1 J domain.
Contains 2 SANT domains.

Database links:

Entrez Gene: 64215 Human

Entrez Gene: 450344 Chimpanzee

Entrez Gene: 607587 Dog

Entrez Gene: 101125129 Gorilla

Entrez Gene: 13418 Mouse

Entrez Gene: 100455306 Orangutan

Entrez Gene: 100519794 Pig

Entrez Gene: 100341962 Rabbit

Entrez Gene: 291369 Rat

Entrez Gene: 704151 Rhesus monkey

Entrez Gene: 444260 Xenopus laevis

Entrez Gene: 496816 Xenopus tropicalis