background:
The protein encoded by this gene belongs to the DNAJ/HSP40 family of proteins that regulate chaperone activity. This family member suppresses aggregation and toxicity of polyglutamine proteins, and the SLCterminal tail is essential for this activity. It has been implicated as a cancer-testis antigen and as a cancer stem-like cell antigen involved in renal cell carcinoma. [provided by RefSeq, Jun 2012]
Similarity:
Contains 1 J domain.
Database links:
Entrez Gene: 518674 Cow
Entrez Gene: 165721 Human
Entrez Gene: 60992 Dog
Entrez Gene: 101149358 Gorilla
Entrez Gene: 500253 Rat
Omim: 611337 Human
SwissProt: Q8NHS0 Human
Unigene: 518241 Human
Unigene: 125884 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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