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Rabbit Anti-DNAJC17/FITC Conjugated antibody
background:
The DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers, forming peptide binding domains responsible for chaperone function. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DNAJC17 (DnaJ (Hsp40) homolog, subfamily C, member 17) is a 304 amino acid protein containing a J domain and a RRM (RNA recognition motif) domain.
Similarity:
Contains 1 J domain.
Contains 1 RRM (RNA recognition motif) domain.
Database links:
Entrez Gene: 55192 Human
Entrez Gene: 524795 Cow
Entrez Gene: 478261 Dog
Entrez Gene: 69408 Mouse
Entrez Gene: 311329 Rat
SwissProt: Q2KI83 Cow
SwissProt: Q9NVM6 Human
SwissProt: Q91WT4 Mouse
Unigene: 511069 Human
Unigene: 222241 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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