Rabbit Anti-DNAJC14/FITC Conjugated antibody

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DJC14_HUMAN; DnaJ (Hsp40) homolog, subfamily C, member 14; DNAJ; DnaJ homolog subfamily C member 14; DnaJ protein homolog 3; DNAJC14; Dopamine receptor interacting protein; Dopamine receptor-interacting protein of 78 kDa; DRiP78; hDj 3; HDJ-3;

Cat:

SL14381R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human DNAJC14

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

79kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. DnaJ proteins are important mediators of proteolysis and are involved in the regulation of protein degradation, exocytosis and endocytosis. DnaJC14 (DnaJ homolog subfamily C member 14), also known as DRIP78 (Dopamine receptor-interacting protein of 78 kDa) and HDJ3 (Human DnaJ protein 3), is a 702 amino acid endoplasmic reticulular membrane protein that contains one J domain. DnaJC14 regulates the export of target proteins, such as the dopamine D1 receptor (D1DR), from the endoplasmic reticulum to the cell surface.

Function:
Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in pancreas and selectively expressed in brain, lung, liver, skeletal muscle and kidney.

Similarity:
Contains 1 J domain.

Database links:

Entrez Gene: 85406 Human

Entrez Gene: 74330 Mouse

Entrez Gene: 114481 Rat

Omim: 606092 Human

SwissProt: Q6Y2X3 Human

SwissProt: Q921R4 Mouse

SwissProt: Q5XIX0 Rat

Unigene: 70964 Human

Unigene: 296915 Mouse

Unigene: 114340 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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