KLH conjugated synthetic peptide derived from human CD3
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Monoclonal
Isotype：
IgG
Applications：
Flow-Cyt=5ul/TestICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Mouse
Calculated MW：
20kDa
Product Overview：
scatter diagram showing peripheral blood lymphocytes stained with SLM30092M-FITC. The cells were incubated with the antibody (SLM30092M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008].
Function: The CD3 complex mediates signal transduction.
Subunit: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
Subcellular Location: Membrane; Single-pass type I membrane protein.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Picture
scatter diagram showing peripheral blood lymphocytes stained with SLM30092M-FITC. The cells were incubated with the antibody (SLM30092M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
