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Home > Product > Antibody > Mouse Anti-CD8/FITC Conjugated antibody
CD8a Molecule; T-Lymphocyte Differentiation Antigen T8/Leu-2; T-Cell Surface Glycoprotein CD8 Alpha Chain; CD8 Antigen, Alpha Polypeptide (P32); MAL; Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen; T-Cell Antigen Leu2; T Cell Co-Receptor; T8 T-Ce
Cat:
SLM30094M-FITC
Species Reactivity：
Human,
Immunogen：
KLH conjugated synthetic peptide derived from human CD8
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Monoclonal
Isotype：
IgG
Applications：
Flow-Cyt=5ul/TestICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Mouse
Calculated MW：
27kDa
Product Overview：
scatter diagram showing peripheral blood lymphocytes stained with SLM30094M-FITC. The cells were incubated with the antibody (SLM30094M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.

Similarity:
Belongs to the PMP-22/EMP/MP20 family.

Database links:

Entrez Gene: 925 Human

Entrez Gene: 926 Human

Entrez Gene: 12525 Mouse

Entrez Gene: 12526 Mouse

Omim: 186910 Human

SwissProt: P01732 Human

SwissProt: P10966 Human

SwissProt: P01731 Mouse

SwissProt: P10300 Mouse

Unigene: 405667 Human

Unigene: 85258 Human

Unigene: 1858 Mouse

Unigene: 333148 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Picture

scatter diagram showing peripheral blood lymphocytes stained with SLM30094M-FITC. The cells were incubated with the antibody (SLM30094M-FITC, 5 µl/Test) for 30 min at 22°C. Acquisition of >10,000 events was performed.
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