Rabbit Anti-phospho-KCNC1 (Ser503) antibody

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KCNC1 (phospho S503); p-KCNC1 (phospho Ser503); C230009H10Rik; FLJ41162; FLJ42249; FLJ43491; Kcr2 1; KShIIIB; Kv3.1; Kv4; MGC129855; NGK2; Potassium voltage-gated channel subfamily C member 1; Shaw; Voltage gated potassium channel; KCNC1_RAT; Voltage gate

Cat:

SL5403R

Species Reactivity：

Human,(predicted: Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated Synthesised phosphopeptide derived from rat KCNC1 around the phosphorylation site of Ser503:AD(p-S)KL

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Product Overview：

Sample: HL60(Human) Cell Lysate at 30 ugPrimary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 58 kDObserved band size: 58 kDSample: Hela(Human) Cell Lysate at 30 ugPrimary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 58 kDObserved band size: 58 kDSample: U2OS(Human) Cell Lysate at 30 ugHela (Human) Cell Lysate at 30 ugPrimary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 58 kDObserved band size: 58 kDSample: HL60(Human) Cell Lysate at 30 ug>Primary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilutionSecondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilutionPredicted band size: 58 kDObserved band size: 58 kD

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Unit:

Price: $256.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2.

Function:
This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Subunit:
Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity).

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.

SWISS:
P25122

Gene ID:
25327

Database links:

Entrez Gene: 3746 Human

Entrez Gene: 16502 Mouse

Entrez Gene: 25327 Rat

Omim: 176258 Human

SwissProt: P48547 Human

SwissProt: P15388 Mouse

SwissProt: P25122 Rat

Unigene: 303870 Human

Unigene: 552896 Human

Unigene: 249386 Mouse

Unigene: 33095 Rat

Picture

Sample:
Hela(Human) Cell Lysate at 30 ug
Primary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD

Sample:
U2OS(Human) Cell Lysate at 30 ug
Hela (Human) Cell Lysate at 30 ug
Primary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD

Sample:
HL60(Human) Cell Lysate at 30 ug
> Primary: Anti- phospho-KCNC1 (Ser503) (SL5403R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD

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