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Rabbit Anti-MAGEA6 antibody
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
Similarity:
Contains 1 MAGE domain.
SWISS:
P4372
Gene ID:
4105
Database links:
Entrez Gene: 4105 Human
Entrez Gene: 17142 Mouse
Omim: 300176 Human
SwissProt: P4372 Human
SwissProt: Q6NW44 Human
Unigene: 441113 Human
Unigene: 377098 Mouse
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