Mouse Anti-human CD8 antibody

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CD8 antigen, alpha polypeptide (p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lympho

Cat:

SLM30094M

Species Reactivity：

(predicted: Human,)

Immunogen：

Recombinant human CD8

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Monoclonal

Isotype：

Mouse IgG1, k

Applications：

Flow-Cyt=5ul/Testnot yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Mouse

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Unit:

Price: $376.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.

Similarity:
Belongs to the PMP-22/EMP/MP20 family.

SWISS:
P01732

Gene ID:
925

Database links:

Entrez Gene: 925 Human

Entrez Gene: 926 Human

Entrez Gene: 12525 Mouse

Entrez Gene: 12526 Mouse

Omim: 186910 Human

SwissProt: P01732 Human

SwissProt: P10966 Human

SwissProt: P01731 Mouse

SwissProt: P10300 Mouse

Unigene: 405667 Human

Unigene: 85258 Human

Unigene: 1858 Mouse

Unigene: 333148 Mouse

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