Rabbit Anti-Reticulon 1/FITC Conjugated antibody

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MGC133250; Neuroendocrine specific protein; NSP; Reticulon 1; Reticulon1; Reticulon1A; RTN 1; RTN1; RTN1 protein; RTN1_HUMAN.

Cat:

SL11798R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human Reticulon 1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

84kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

Function:
May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.

Subunit:
Interacts with NDRG1.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.

Post-translational modifications:
Isoforms RTN1-A and RTN1-B are phosphorylated.

Similarity:
Contains 1 reticulon domain.

Database links:

Entrez Gene: 6252 Human

Entrez Gene: 116644 Rat

Omim: 600865 Human

SwissProt: Q16799 Human

SwissProt: Q64548 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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