Rabbit Anti-FLAD1/FITC Conjugated antibody

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FAD pyrophosphorylase; FAD synthetase; FAD synthetase region; FAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae); Fad1, flavin adenine dinucleotide synthetase, homolog; Fad1, flavin adenine dinucleotide synthetase, homolog (yeast);

Cat:

SL11691R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Zebrafish,)

Immunogen：

KLH conjugated synthetic peptide derived from human FLAD1 (345-420aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

65kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
FLAD1 is a 587 amino acid protein where its N-terminus belongs to the moaB/mog family and its SLCterminus belongs to the PAPS reductase family. Existing as five alternatively spliced isoforms, FLAD1 localizes to the cytoplasm and utilizes magnesium as a cofactor. FLAD1 is a key enzyme in the metabolic pathway that converts riboflavin into the redox cofactor flavin adenine dinucleotide (FAD). It is suggested that the molybdenum cofactor biosynthesis protein-like region of FLAD1 may not be functional.

Function:
FLAD1 catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Subcellular Location:
Cytoplasmic

Similarity:
In the N-terminal section; belongs to the MoaB/Mog family.
In the SLCterminal section; belongs to the PAPS reductase family. FAD1 subfamily.

Database links:
UniProtKB/Swiss-Prot: Q8NFF5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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