Rabbit Anti-Gbx1/FITC Conjugated antibody

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Gastrulation and brain specific homeobox protein 1; Gastrulation and brain-specific homeobox protein 1; Gastrulation brain homeo box 1; Gastrulation brain homeobox 1; Gbx1; GBX1_HUMAN; Homeobox protein GBX-1; Homeobox protein GBX1.

Cat:

SL11660R-FITC

Species Reactivity：

Mouse,Rat,(predicted: Human,Chicken,Dog,Pig,Rabbit,Zebrafish,Sheep,Fruit Fly,Chimpanzee,mpanzee,)

Immunogen：

KLH conjugated synthetic peptide derived from human Gbx1 (201-300aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

38kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The homeobox is DNA sequence that is approximately 36 base pairs long that is involved in all steps of the developmental regulation of animals, fungi and plants, from embryogenesis to cell differentiation. The homeobox encodes a protein domain of about 60 amino acids, called the homeodomain, that can bind to DNA. The gastrulation brain homeobox 1 (GBX1) gene, along with another homeobox gene (EN2), maps to chromosome 7q36, and is expressed in septal and pallidal areas and in the basal forebrain cholinergic system, an area implicated in Alzheimer’s disease. The GBX1 gene encodes the GBX1 protein, which localizes to the nucleus and contains 1 homeobox DNA-binding domain.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 2636 Human

Entrez Gene: 231044 Mouse

Entrez Gene: 246149 Rat

Omim: 603354 Human

SwissProt: Q14549 Human

SwissProt: P82976 Mouse

Unigene: 647114 Human

Unigene: 246596 Mouse

Unigene: 92432 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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