Rabbit Anti-APPBP2/FITC Conjugated antibody

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amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein binding protein 2; Amyloid protein-binding protein 2; APBP2_HUMAN; APP BP2; APP-BP2; Appbp2; PAT1; Ara67 Protein interac

Cat:

SL11639R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Zebrafish,)

Immunogen：

KLH conjugated synthetic peptide derived from human APPBP2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

67kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq, Jul 2008].

Function:
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.

Subunit:
Binds APP.

Subcellular Location:
Nucleus. Cytoplasm

Post-translational modifications:
Rapidly degraded by the proteasome upon overexpression of a SLCterminal fragment of APP.

Similarity:
Contains 8 TPR repeats.

Database links:

Entrez Gene: 10513 Human

Entrez Gene: 66884 Mouse

Entrez Gene: 303396 Rat

Entrez Gene: 417645 Chicken

Omim: 605324 Human

SwissProt: Q92624 Human

SwissProt: Q9DAX9 Mouse

SwissProt: A5HK05 Rat

Unigene: 16884 Human

Unigene: 271997 Mouse

Unigene: 104856 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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