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Home > Product > Antibody > Rabbit Anti-RGS21/FITC Conjugated antibody
Regulator of G-protein signaling 21; RGS21; RGS21_HUMAN.
Cat:
SL11620R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human RGS21
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
18kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008].

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.

Tissue Specificity:
Expressed ubiquitously.

Similarity:
Contains 1 RGS domain.

Database links:

Entrez Gene: 431704 Human

Omim: 61487 Human

SwissProt: Q2M5E4 Human

Unigene: 558673 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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