Rabbit Anti-RTP3/FITC Conjugated antibody

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LTM1; Receptor (chemosensory) transporter protein 3; Receptor transporter protein 3; Receptor-transporting protein 3; RTP3; RTP3_HUMAN; TMEM7; Transmembrane protein 7.

Cat:

SL11619R-FITC

Species Reactivity：

(predicted: Human,Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human RTP3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

27kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Members of the RTP (receptor transporter proteins) family have recently been discovered to influence bitter taste receptor expression in addition to inducing the expression of mammalian odorant receptors. RTP3 is a 232 amino acid single-pass type III membrane protein belonging to the TMEM7 family. Unlike other RTP proteins, RTP3 is not expressed in olfactory neurons but is expressed predominantly in liver. RTP3 is involved in the functional expression of bitter taste receptors and suppresses cell proliferation, and is also found in human circumvallate papillae and testis (regions where bitter taste receptors are expressed). The gene encoding RTP3 maps to human chromosome 3p21.31 within C3CER1 (chromosome 3 common eliminated region 1), which is frequently eliminated in chromosomal deletions of solid tumors.

Function:
Expressed predominantly in the liver.

Subcellular Location:
Membrane; Single-pass type III membrane protein

Tissue Specificity:
Belongs to the TMEM7 family.

Similarity:
Belongs to the TMEM7 family.

Database links:
UniProtKB/Swiss-Prot: Q9BQQ7.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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