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Rabbit Anti-TAS2R5/FITC Conjugated antibody
background:
This gene encodes a bitter taste receptor; bitter taste receptors are members of the G protein-coupled receptor superfamily and are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless taste receptor genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes on chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008].
Function:
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLSLCbeta-2 activation and lead to the gating of TRPM5.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.
Similarity:
Belongs to the G-protein coupled receptor T2R family.
Database links:
Entrez Gene: 54429 Human
Omim: 605062 Human
SwissProt: Q9NYW4 Human
Unigene: 675370 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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