Rabbit Anti-SOX6/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-SOX6/FITC Conjugated antibody

HSSOX 6; HSSOX6; SOX-6 SOX 6; SOX6_HUMAN.

Cat:

SL11599R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SOX6 (1-100aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

92kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation.

Subunit:
Interacts with DAZAP2

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in a wide variety of tissues, most abundantly in skeletal muscle.

Post-translational modifications:
Sumoylation inhibits the transcriptional activity.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 55553 Human

Entrez Gene: 20679 Mouse

Entrez Gene: 293165 Rat

Omim: 607257 Human

SwissProt: P35712 Human

SwissProt: P40645 Mouse

SwissProt: Q8BSS6 Mouse

SwissProt: Q4V8G3 Rat

Unigene: 368226 Human

Unigene: 323365 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall