Rabbit Anti-NAT8 + NAT8B/FITC Conjugated antibody

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NAT8+NAT8B; Camello-like protein 1; NAT8; NAT8_HUMAN; Probable N-acetyltransferase 8; Camello like protein 2; Camello-like protein 2; CML2; Hcml2; N acetyltransferase 8B; NAT8B; NAT8B_HUMAN; NAT8BP; Probable N acetyltransferase 8B; Probable N-acetyltransf

Cat:

SL11591R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human NAT8 (141-220aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

26kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
NAT8 gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008].
NAT8B protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008].

Function:
Plays a role in regulation of gastrulation.

Subcellular Location:
Membrane.

Tissue Specificity:
Expression is restricted to liver and kidney.

Similarity:
Belongs to the camello family.
Contains 1 N-acetyltransferase domain.

Database links:

Entrez Gene: 9027 Human

Entrez Gene: 51471 Human

NCBI: NP_057431 Human

Omim: 606716 Human

Omim: 608190 Human

SwissProt: Q9UHE5 Human

SwissProt: Q9UHF3 Human

Unigene: 14637 Human

Unigene: 728429 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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