Rabbit Anti-SOX13/FITC Conjugated antibody

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ICA 12; ICA12; Islet cell antibody 12; Islet cell antigen 12; MGC117216; SOX 13; SOX 13 protein; sox13; SOX13 protein; SOX13_HUMAN; SRY (Sex determining region Y)-box 13; SRY box 13; SRY box containing gene 13; SRY related HMG box gene 13; SRY sex determi

Cat:

SL11586R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human ICA12 (401-500aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

69kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12. [provided by RefSeq, Jul 2008]

Function:
Binds to the sequence 5'-AACAAT-3'.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in kidney, lung, and liver and low expression in thymus, brain, spleen, and muscle.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 9580 Human

Entrez Gene: 20668 Mouse

Entrez Gene: 289026 Rat

Omim: 604748 Human

SwissProt: Q9UN79 Human

SwissProt: Q04891 Mouse

Unigene: 201671 Human

Unigene: 8575 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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