Home > Product > Antibody > Rabbit Anti-SORCS3/FITC Conjugated antibody
6330404A12Rik; KIAA1059; RP11 107L7.1; SORC3_HUMAN; SORCS 3; SORCS; SORCS3; Sortilin related VPS10 domain containing receptor 3; VPS10 domain containing receptor SorCS3; VPS10 domain receptor protein SORCS 3; VPS10 domain-containing receptor SorCS3.
Cat:
SL11503R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human SORCS3
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
132kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Highly expressed in brain.

Similarity:
Belongs to the VPS10-related sortilin family. SORCS subfamily.
Contains 6 BNR repeats.
Contains 1 PKD domain.

Database links:
UniProtKB/Swiss-Prot: Q9UPU3.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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