Rabbit Anti-PTPRD/FITC Conjugated antibody

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protein tyrosine phosphatase receptor type D; RPTP Delta; Tyrosine phosphatase Delta; PTPRD_HUMAN.

Cat:

SL11471R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PTPRD (783-830aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

212kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
RelevancePTPRD is a protein tyrosine phosphatase that falls into the receptor-type group as it characteristically comprises an extracellular region, a single transmembrane region and two tandem cytoplasmic catalytic domains. The extracellular region of this protein contains 3 Ig-like and 8 fibronectin type III-like domains. This protein is thought to be involved in promoting neurite growth and in axonal guidance.

Subunit:
Interacts with IL1RAPL1 (via extracellular region); interaction is required for IL1RAPL1-mediated synapse formation (By similarity). Interacts with PPFIA1, PPFIA2 and PPFIA3.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Post-translational modifications:
A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization.

Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Contains 8 fibronectin type-III domains.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 tyrosine-protein phosphatase domains.

Database links:

Entrez Gene: 5789 Human

Omim: 601598 Human

SwissProt: P23468 Human

Unigene: 49283 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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