Rabbit Anti-TXNDC11/FITC Conjugated antibody

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EF-hand-binding protein 1; EFP1; RGD1307538; Thioredoxin domain-containing protein 11; TXD11_HUMAN; TXNDC11; 2810408E11Rik; AI427833.

Cat:

SL11439R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TXNDC11

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

110kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.

Function:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.

Subunit:
Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Widely expressed at low level. Expressed at higher level in thyroid and prostate.

Similarity:
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.

Database links:

Entrez Gene: 98003 Dog

Entrez Gene: 100056118 Horse

Entrez Gene: 51061 Human

SwissProt: Q6PKC3 Human

Unigene: 313847 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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