Home > Product > Antibody > Rabbit Anti-Adrenodoxin/FITC Conjugated antibody
Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.
Cat:
SL11426R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX (51-150aa)
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
13.5kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

Database links:

Entrez Gene: 2230 Human

Entrez Gene: 14148 Mouse

Entrez Gene: 29189 Rat

Omim: 103260 Human

SwissProt: P10109 Human

SwissProt: P46656 Mouse

SwissProt: P24483 Rat

Unigene: 744 Human

Unigene: 1061 Mouse

Unigene: 88190 Mouse

Unigene: 6946 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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