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Rabbit Anti-Adrenodoxin/FITC Conjugated antibody
background:
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]
Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.
Subcellular Location:
Mitochondrion matrix.
Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.
Database links:
Entrez Gene: 2230 Human
Entrez Gene: 14148 Mouse
Entrez Gene: 29189 Rat
Omim: 103260 Human
SwissProt: P10109 Human
SwissProt: P46656 Mouse
SwissProt: P24483 Rat
Unigene: 744 Human
Unigene: 1061 Mouse
Unigene: 88190 Mouse
Unigene: 6946 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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