Home > Product > Antibody > Rabbit Anti-Sauvagine/FITC Conjugated antibody
Sauvagin; Sauvagine; SVG; SAUV_PHYSA.
Cat:
SL11424R-FITC
Immunogen:
KLH conjugated synthetic peptide derived from frog Sauvagine (C-QGPPISIDLSLELLRKMIEIEKQEKEKQQAANNRLLLDTI-NH2)
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
4.6kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Sauvagine is a 40-residue peptide isolated and characterized from frog skin. It shares significant structural homology with and elicits similar biological responses as corticotropin-releasing factor (CRF). It has high affinity for both the CRF1 and CRF2 receptors (and low affinity for the CRF binding protein), suggesting its potential as a pharmacological tool for the study of these receptor sub-types. Due to the binding to CRF2 receptors and their role in the release of ACTH and beta-endorphin during stress, possible areas of research with this ligand include anxiety, depression and obesity.

Function:
Hypotensive and diuretic peptide.

Subcellular Location:
Secreted.

Similarity:
Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

Database links:
UniProtKB/Swiss-Prot: P01144.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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