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Rabbit Anti-TSPEAR/FITC Conjugated antibody
background:
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
Function:
C21orf91 belongs to the EURL family. There are three named isoforms. The exact function of C21orf91 remains unknown.
Subcellular Location:
Secreted.
Similarity:
Contains 7 EAR repeats.
Contains 1 laminin G-like domain.
Database links:
Entrez Gene: 54149 Human
Entrez Gene: 67102 Mouse
Entrez Gene: 72692 Rat
SwissProt: Q9NYK6 Human
SwissProt: Q9D7G4 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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