Rabbit Anti-rSec6/FITC Conjugated antibody

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EXOC 3; EXOC3; Exocyst complex component 3; Exocyst complex component Sec 6; Exocyst complex component Sec6; rSec 6; Sec 6; Sec-6; Sec 6 homolog; Sec 6p; Sec6; SEC6 L1; SEC6 like 1; Sec6 protein; SEC6L1; Sec6p; EXOC3_HUMAN.

Cat:

SL11396R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human rSec6 (714-756aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

87kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Function:
Sec6 is a component of the exocyst complex involved in the docking of exocystic vesicles with fusions site on the plasma membrane.

Subunit:
The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with EXOC3L1 (By similarity). Interacts with BIRC6/bruce. Interacts with MYRIP

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the SEC6 family.

Database links:

Entrez Gene: 11336 Human

Entrez Gene: 211446 Mouse

Entrez Gene: 252881 Rat

Omim: 608186 Human

SwissProt: O60645 Human

SwissProt: Q6KAR6 Mouse

SwissProt: Q62825 Rat

Unigene: 481464 Human

Unigene: 489612 Mouse

Unigene: 6753 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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