background:
Syntenin-2 is a 292 amino acid protein that contains two PDZ (DHR) domains and functions as either a monomer or a homodimer that interacts with syntenin-1. Multiple isoforms of syntenin-2 exist and are encoded by a gene which maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Subunit:
Monomer and homodimer. Interacts with SDCBP (By similarity).
Similarity:
Contains 2 PDZ (DHR) domains.
Database links:
UniProtKB/Swiss-Prot: Q9H190.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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