Rabbit Anti-SNAP23/FITC Conjugated antibody

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SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membr

Cat:

SL11362R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human SNAP23

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

23kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Subunit:
Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A.

Subcellular Location:
Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane.

Tissue Specificity:
Ubiquitous. Highest levels where found in placenta.

Similarity:
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains.

Database links:

Entrez Gene: 453365 Chimpanzee

Entrez Gene: 522423 Cow

Entrez Gene: 478268 Dog

Entrez Gene: 101141000 Gorilla

Entrez Gene: 8773 Human

Entrez Gene: 20619 Mouse

Entrez Gene: 100174679 Orangutan

Entrez Gene: 64630 Rat

Omim: 602534 Human

SwissProt: O00161 Human

SwissProt: O09044 Mouse

SwissProt: O70377 Rat

Unigene: 511149 Human

Unigene: 245715 Mouse

Unigene: 14789 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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