Rabbit Anti-Glycophorin A/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-Glycophorin A/FITC Conjugated antibody

Glycophorin A; AI853584; CD235a; GPA; Blood group-MN locus; CD235a antigen; Glycophorin A (MNS blood group); Glycophorin A includes MN blood group; Glycophorin A precursor; Glycophorin A, included; GlycophorinA; GPA; GPErik; GpMiIII; GPSAT; GYPA; GYPA, in

Cat:

SL10017R-FITC

Species Reactivity：

Human,

Immunogen：

KLH conjugated synthetic peptide derived from human CD235a

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

14kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008].

Function:
Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).

Subunit:
Homodimer. Interacts with Streptococcus gordonii has protein.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Note=Appears to be colocalized with SLC4A1.

Similarity:
Belongs to the glycophorin A family.

Database links:

Entrez Gene: 2993 Human

Entrez Gene: 14934 Mouse

Omim: 111300 Human

SwissProt: P02724 Human

SwissProt: P14220 Mouse

Unigene: 434973 Human

Unigene: 13123 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall