background:
The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, one mechanism of controlling translation, is driven by cytoplasmic polyadenylation element binding proteins, called CPEBs. CPEB3 (cytoplasmic polyadenylation element binding protein 3) is a 698 amino acid protein that contains two RNA recognition motif (RRM) domains and, like other CPEB proteins, may play a role in the maturation of the central nervous system. CPEB3 exists as multiple alternatively spliced isoforms that are encoded by a gene which maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome.
Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.
Database links:
Entrez Gene: 22849 Human
Entrez Gene: 208922 Mouse
SwissProt: Q8NE35 Human
SwissProt: Q7TN99 Mouse
Unigene: 131683 Human
Unigene: 701732 Human
Unigene: 371677 Mouse
Unigene: 391176 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|
