Home > Product > Antibody > Rabbit Anti-NPTX1/FITC Conjugated antibody
Neuronal pentraxin I; Neuronal pentraxin-1; NP 1; NP-I; NP1; Nptx1; NPTX1_HUMAN.
Cat:
SL4893R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human NPTX1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
45kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system.

Function:
May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.

Subcellular Location:
Cytoplasmic vesicle, secretory vesicle (Potential).

Similarity:
Contains 1 pentaxin domain.

Database links:

Entrez Gene: 4884 Human

Entrez Gene: 18164 Mouse

Entrez Gene: 266777 Rat

Omim: 602367 Human

SwissProt: Q15818 Human

SwissProt: Q62443 Mouse

SwissProt: P47971 Rat

Unigene: 514556 Human

Unigene: 719136 Human

Unigene: 5142 Mouse

Unigene: 54707 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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