Rabbit Anti-Parvovirus Capsid protein VP1/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-Parvovirus Capsid protein VP1/FITC Conjugated antibody

Parvovirus h-1 coat; CAPSD_PAVHH; Capsid protein VP1; Coat protein VP1; H-1 Parvovirus Capsid protein VP1.

Cat:

SL4649R-FITC

Immunogen：

KLH conjugated synthetic peptide derived from H-1 parvovirus Capsid protein VP1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

81kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

Function:
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

Subcellular Location:
Virion. Host nucleus.

Similarity:
Belongs to the parvoviridae capsid protein family.

Database links:
UniProtKB/Swiss-Prot: P03136

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

大鼠H-1病毒株是由Toolan(1960)从经大鼠传代的人肿瘤细胞系(HEP-1)分离到得第2株大鼠细小病毒(RPV),通常称为H-1病毒,又称Toolan病毒。

Product Feedback Wall