Home > Product > Antibody > Rabbit Anti-Cardiac FABP/FITC Conjugated antibody
Muscle fatty acid binding protein; 422 protein; Cardiac Fatty Acid Binding Protein; FABP 11; FABP 3; FABP11; FABP3; FABPH_HUMAN; Fatty acid binding protein 11; Fatty acid binding protein 3; Fatty acid binding protein 3 muscle and heart; Fatty acid binding
Cat:
SL11283R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human FABP3
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
15kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). MDGI is highly expressed in the myocardium, skeletal and smooth muscle fibers, lipid and/or steroid synthesizing cells and terminally differentiated epithelia of the respiratory, intestinal and urogenital tracts.

Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Database links:

Entrez Gene: 2170 Human

Entrez Gene: 14077 Mouse

Entrez Gene: 79131 Rat

Omim: 134651 Human

SwissProt: P05413 Human

SwissProt: P11404 Mouse

SwissProt: P07483 Rat

Unigene: 657242 Human

Unigene: 388886 Mouse

Unigene: 32566 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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