background:
CEBP gamma is a transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. It might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.
Function:
Transcription factor that binds to the promoter and the enhancer of the immunoglobulin heavy chain. Binds to GPE1, a cis-acting element in the G-CSF gene promoter.
Subunit:
Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and beta. Interacts with ZNF638; this interaction increases transcriptional activation.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the bZIP family. C/EBP subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.
Database links:
UniProtKB/Swiss-Prot: P53568.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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