Rabbit Anti-gamma crystallin S/FITC Conjugated antibody

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rncat; AI327013; Beta-crystallin S; CRBS_HUMAN; CRYG8; crygs; Crystallin, gamma 8; Crystallin, gamma polypeptide 8; Crystallin, gamma S; Gamma crystallin S; Gamma S crystallin; Gamma-crystallin S; Gamma-S-crystallin; Opacity due to poor secondary fiber ce

Cat:

SL9585R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human gamma crystallin S(121-168aa)

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

20kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Crystallins are water soluble structural proteins found in the vertebrate eye. Mammalian crystallins are classified in three forms, designated α, β and γ. Crystallins, as the principal components of the lens, function to increase the refractive index of the eye during accommodation by forming high-molecular weight aggregates which maintain transparency. γS-crystallin (Gamma-crystallin S), also known as Beta-crystallin S, is a 178 amino acid protein that exists as a monomer which does not aggregate. γS-crystallin contains a two-domain beta structure and belongs to the beta/gamma-crystallin gene family mapping to human chromosome 3. γS-crystallin has been linked to congenital cataract development, a disorder signified by increasing levels of lens opacity.

Function:
Crystallins are the dominant structural components of the vertebrate eye lens.

Subunit:
Monomer.

Subcellular Location:
Has a two-domain beta-structure, folded into four very similar Greek key motifs.

Similarity:
Belongs to the beta/gamma-crystallin family.
Contains 4 beta/gamma crystallin 'Greek key' domains.

Database links:

Entrez Gene: 1427 Human

Entrez Gene: 12970 Mouse

Entrez Gene: 689897 Rat

Omim: 123730 Human

SwissProt: P06504 Cow

SwissProt: P22914 Human

SwissProt: O35486 Mouse

SwissProt: P0C5E9 Rat

Unigene: 376209 Human

Unigene: 6253 Mouse

Unigene: 198271 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

γS-crystallin

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