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Rabbit Anti-PCDHGA3/FITC Conjugated antibody
background:
PCDHGA3 is a 932 amino acid that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA3 is a member of the gamma subfamily A. PCDHGA3 is a type I transmembrane receptor containing six cadherin motifs and is expressed in the central nervous system where it localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. There are two isoforms of PCDHGA3 that are produced as a result of alternative splicing events.
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Location:
Cell membrane.
Similarity:
Contains 6 cadherin domains.
Database links:
Entrez Gene: 56112 Human
Omim: 606290 Human
SwissProt: Q9Y5H0 Human
Unigene: 368160 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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