Rabbit Anti-NPTX2/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-NPTX2/FITC Conjugated antibody

apexin; NARP; Neuronal pentraxin 2; Neuronal pentraxin II; Neuronal pentraxin-2; NP 2; NP-II; NP2; NPII; NPTX2; NPTX2_HUMAN.

Cat:

SL11017R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Dog,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human NPTX2

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

46kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
Long pentraxins are a family of highly conserved proteins that are expressed in the brain and central nervous system, and form multimeric complexes. Neuronal pentraxin 1 (NP1), NP2, and neuronal pentraxin receptor (NPR) are members of the long pentraxins that represent a neuronal uptake pathway that may function during synapse formation and remodeling. The NP1 gene is located on chromosome 17q25.3 and the protein product mediates the uptake of synaptic material, including the presynaptic snake venom toxin, taipoxin (3). NP2, whose function is unknown, is located on chromosome 7q22.1 and like NP1 contains several potential N-linked glycosylation sites. NPR is expressed on the cell membrane and can form heteropentamers with NP1 and NP2 that can be released from the cell membrane by proteolysis.

Function:
Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.

Subunit:
Homooligomer or heterooligomer (probably pentamer) with neuronal pentraxin receptor (NPTXR).

Subcellular Location:
Secreted.

Tissue Specificity:
Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.

Similarity:
Contains 1 pentaxin domain.

Database links:

Entrez Gene: 4885 Human

Entrez Gene: 53324 Mouse

Entrez Gene: 288475 Rat

Omim: 600750 Human

SwissProt: P47972 Human

SwissProt: O70340 Mouse

SwissProt: P97738 Rat

Unigene: 3281 Human

Unigene: 10099 Mouse

Unigene: 162101 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall