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Rabbit Anti-ILVBL/FITC Conjugated antibody
background:
ILVBL is a 632 amino acid single-pass membrane protein that belongs to the TPP enzyme family. Expressed in the majority of tissues, ILVBL has the highest level of expression in heart, pancreas and placenta. ILVBL is highly homologous to several bacterial enzymes, including the B isozyme of the large catalytic subunit of E. coli acetohydroxy-acid synthase (AHAS) and the oxalyl-coA decarboxylase of O. formigenes, that utilize thiamine pyrophosphate as a cofactor. ILVBL binds one magnesium ion and one thiamine pyrophosphate per subunit, and may catalyze the initial step in branched-chain amino acid biosynthesis. The gene encoding ILVBL maps to human chromosome 19p13.12 and mouse chromosome 10 C1.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in all tissues tested, with highest expression in heart, pancreas and placenta.
Similarity:
Belongs to the TPP enzyme family.
Database links:
Entrez Gene: 10994 Human
Omim: 605770 Human
SwissProt: A1L0T0 Human
Unigene: 78176 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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