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Rabbit Anti-LACTB2/FITC Conjugated antibody
background:
Penicillin refers to any member of beta-lactam antibiotics group. These agents are identified by a beta-lactam ring within their molecular structure. As the most widely used group of antibiotics available, beta-lactams are used for the treatment of bacterial infections usually caused by gram-positive organisms. Beta-lactam antibiotics are bactericidal, functioning to inhibit the synthesis of the peptidoglycan layer of bacterial cell walls. Bacterial penicillin-binding proteins and beta-lactamases constitute a large family of serine proteases that perform essential functions in the synthesis and maintenance of peptidoglycan cell wall. Notably, beta-lactamases cleave beta-lactams, therefore providing the bacteria with resistance to the antibiotic. Homologues of beta-lactamases occur in many species, including human, rat, cow, rabbit, pig, xenopus, zebrafish, and C. elegans. The human homologues, LACTB and LACTB2, are active-site-serine enzymes thought to be involved in metabolism.
Similarity:
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Database links:
Entrez Gene: 51110 Human
SwissProt: Q53H82 Human
Unigene: 118554 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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