Rabbit Anti-C7orf27/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-C7orf27/FITC Conjugated antibody

BAAT 1; BAAT1; BRAT-1; brat1; BRAT1_HUMAN; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1; BRCA1-associated protein required for ATM activation-1; C7orf27; chromosome 7 open reading frame 27; HEAT repeat c

Cat:

SL9542R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human BAAT1/C7orf27

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

88kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

Function:
Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM.

Subunit:
Interacts with BRCA1 and ATM.

Subcellular Location:
Nucleus. Present at double strand breaks (DSBs) following ionizing radiation treatment.

Tissue Specificity:
Ubiquitously expressed.

DISEASE:
Defects in BRAT1 are the cause of rigidity and multifocal seizure syndrome, lethal neonatal (RMFSL) [MIM:614498]. A lethal, neonatal, neurologic disorder characterized by episodic jerking that is apparent in utero, lack of psychomotor development, axial and limb rigidity, frequent multifocal seizures, and dysautonomia. At birth, affected individuals have small heads, overlapping cranial sutures, small or absent fontanels, and depressed frontal bones. Infants show poorly responsive focal jerks of the tongue, face and arms in a nearly continuous sequence throughout life.

Similarity:
Contains 2 HEAT repeats.

Database links:

Entrez Gene: 221927 Human

Entrez Gene: 231841 Mouse

SwissProt: Q6PJG6 Human

SwissProt: Q8C3R1 Mouse

SwissProt: D3ZUM1 Rat

Unigene: 520623 Human

Unigene: 271932 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall